Vacation rentals in Orangeburg County

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Top-rated vacation rentals in Orangeburg County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Home in Summerton

4.86 out of 5 average rating, 153 reviews

Cozy Lake Living

Cozy home on Taw Caw Creek area of Lake Marion with two bedrooms with double beds and a front room with a king bed that overlooks the water. Full kitchen with electric range, microwave, Keurig and regular coffee maker, toaster, refrigerator, dishes, silverware, pots and pans. Living room has a loveseat, couch, WiFi, Roku TV and DVD player. Bathroom has a walk-in shower, no tub. Pets and Parties are NOT allowed. No smoking or vaping inside. Washer and dryer are located under the main living area.

Jul 10 – 17

$115 per night
Guest favorite

Cabin in Rowesville

4.94 out of 5 average rating, 81 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Aug 6 – 13

$42 per night
Guest favorite

Home in Orangeburg

5.0 out of 5 average rating, 61 reviews

centrally located w/coffee bar, theatre/gameroom

Bring the whole family to this newly renovated 3 BR, 2 bath home with lots of room for fun. *Coffee/beverage/snack bar *Theatre/game room Located within five minutes or less to SC State and Claflin University, OC Tech College, Edisto Gardens, hospital, shopping, dining, and more). (Some shopping and dining are within walking distance.) *Designated office space *One king bed, 2 queen beds, plus two queen sleeper sofa’s (in theatre/game room) *5 Roku Smart TV’s *Smart lock for easy entry

Feb 5 – 12

$184 per night

Popular amenities for Orangeburg County vacation rentals

Other great vacation rentals in Orangeburg County

Guest favorite

Home in Orangeburg

4.9 out of 5 average rating, 30 reviews

Charming Furnished Apartment

Apr 28 – May 5

$101 per night
Superhost

Home in Orangeburg

4.92 out of 5 average rating, 12 reviews

Ron's Siesta Airbnb

Nov 23 – 30

$121 per night
Guest favorite

Home in Barnwell

5.0 out of 5 average rating, 33 reviews

Oak View

Jun 17 – 24

$115 per night
Guest favorite

Vacation home in Orangeburg

4.96 out of 5 average rating, 45 reviews

Cozy-Modern Retreat with outdoor entertainment

Feb 28 – Mar 7

$164 per night
Guest favorite

Home in Denmark

4.92 out of 5 average rating, 90 reviews

Lowcountry river life

Apr 16 – 21

$165 per night
Guest favorite

Tiny home in Blackville

4.94 out of 5 average rating, 93 reviews

Spanish Moss (Carolina Cottage)

Jul 7 – 14

$90 per night
Guest favorite

Home in Pinewood

4.97 out of 5 average rating, 36 reviews

Ultimate Hideaway in the pines next to Lake Marion

Jan 24 – 31

$112 per night
Guest favorite

Cottage in Bamberg

4.91 out of 5 average rating, 34 reviews

Rustic Cabin, 300 acres, gated, 2 BR/2 BA, All new

Apr 21 – 28

$116 per night
Guest favorite

Home in Summerton

5.0 out of 5 average rating, 77 reviews

Cheerful 3 bedroom home on the lake

Jan 5 – 12

$149 per night
Guest favorite

Home in Elloree

5.0 out of 5 average rating, 22 reviews

Lured Away to our lakefront home

Sep 27 – Oct 4

$172 per night
Guest favorite

Apartment in Barnwell

5.0 out of 5 average rating, 18 reviews

Dogwood Retreat

Sep 21 – 28

$79 per night
Guest favorite

Home in Orangeburg

5.0 out of 5 average rating, 37 reviews

Colonial Farmhouse - 6 bedroom with a pool

Feb 9 – 16

$244 per night

Destinations to explore