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Panama vacation rentals

Book unique homes, vacation rentals, and more on Airbnb

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Top-rated vacation rentals in Panama

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Guest favorite
Treehouse in Isla Colon
Secret Jungle Treehouse by the Sea
This is 1 of our 2 treehouses: 2 bedrooms; built around a huge tree overlooking the lush jungle in a hidden setting. Artistically designed & comfortable; welcoming romantic souls, nature lovers & the adventurous. Enjoy nature in the harmony of an eco environment; ocean breezes, sound of waves, birds & monkeys. Spectacular sandy beaches only steps away. Surf, swim, bike, explore & live the adventure!. (2nd TREEHOUSE: https://www.airbnb.com/rooms/19376873? YouTube « Jungle Treehouse by the sea »
May 20 – 27
$223 per night
Superhost
Earthen home in El Cope, Penonome
Beautiful Eco House in Panama
We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.
Jun 2 – 9
$185 per night
Guest favorite
Home in Playa Venao
Beautiful Home Directly on Playa Venao Sleeps 8-10
This is our personal home and we take good care to make sure you thoroughly enjoy your stay! This home is located on the best surfing beach in the entire country. Walk out of your back door onto the sandy beach filled with wildlife and the best beach break for beginners to pros. This home offers luxury accommodations. This home is for families and respectful renters only. We do not accept groups who want to use the home to party.
Apr 23 – 30
$565 per night

Popular amenities for Panama vacation rentals

Panama homes

Guest favorite
Home in Bocas del Toro District
Orange House - Over The Water Rentals
Sep 22 – 29
$124 per night
Superhost
Home in Vista Mar Golf, Beach & Marina
Luxurious Beach House - Private Pool Golf & Marina
Feb 9 – 16
$747 per night
Guest favorite
Home in Taboga Island
Casa Rosie - Taboga dream home
Jun 13 – 20
$242 per night
Guest favorite
Home in Las Colinas de Caceres de Arraijan
Tropical Haven with Yoga Platform
Aug 5 – 12
$275 per night
Guest favorite
Home in Panamá
Private Studio 10 Min from the airport !
Mar 22 – 29
$36 per night
Guest favorite
Home in Pedasí
3 min to Pedasi, 5 min to the Beach, Private Pool!
May 5 – 12
$119 per night
Guest favorite
Home in Los Algarrobos
New house! 5 min from David on the Boquete highway
Oct 18 – 25
$63 per night
Superhost
Home in Bajo Boquete
Secluded Riverfront Home - Boquete area with Pool
Oct 29 – Nov 5
$76 per night
Superhost
Home in El Valle de Antón
Casa Antares
Aug 27 – Sep 3
$36 per night
Guest favorite
Home in Panama
Villa Isabella in Coronado Beach Panama
Oct 20 – 27
$313 per night
Guest favorite
Home in El Valle de Antón
Rustic family mountain home - 5 min walk to town!
Apr 30 – May 7
$97 per night
Guest favorite
Home in Playa Venao
Casa Samambaia - sea view tropical paradise w pool
Jun 28 – Jul 5
$286 per night

Panama condominium rentals

Guest favorite
Condo in Panama
Patty’s Cozy & Quiet Studio with K-bed in Casco
Jun 20 – 27
$95 per night
Guest favorite
Condo in Panamá
Spacious Executive Apartment
Dec 5 – 12
$86 per night
Guest favorite
Condo in Panamá
Cozy two bedroom apartment
Jun 6 – 13
$77 per night
Guest favorite
Condo in Panamá
Los Diamantes "Terraza" - ideally located
Jul 28 – Aug 4
$203 per night
Guest favorite
Condo in Panamá
Excellent complete apartment, Panamá, Panamá
Dec 28 – Jan 4
$200 per night
Superhost
Condo in Maria Chiquita
Playa Escondida , Paraíso en Colón/private beach
Nov 20 – 27
$410 per night
Guest favorite
Condo in Panamá
Luxury apartment in the heart of Casco Antiguo
Mar 2 – 9
$93 per night
Guest favorite
Condo in Panama City
Park View Luxury Apartment
Oct 18 – 25
$129 per night
Guest favorite
Condo in Maria Chiquita
Relaxation by the sea
Oct 26 – Nov 2
$69 per night
Superhost
Condo in Panamá
Cozy Unit with Balcony in Santa Ana, Casco Viejo
May 8 – 15
$43 per night
Guest favorite
Condo in San Carlos District
Punta Caelo beachfront apartment San Carlos
Aug 20 – 27
$140 per night
Guest favorite
Condo in Chame
Exclusive Beachfront apartment 1Hour from Pma City
Jun 24 – Jul 1
$168 per night

Other great vacation rentals in Panama

Guest favorite
Townhouse in Panama
Unique Historic House in Casco
Aug 8 – 15
$563 per night
Superhost
Bungalow in Bocas del Toro
Romantic Over the Water Bungalow with Floating Bed
Dec 10 – 17
$120 per night
Guest favorite
Cottage in Bocas del Toro Province
Rustic cottage-Ocean views/walk to surfing/Jungle
Dec 10 – 17
$112 per night
Guest favorite
Apartment in Panamá
Modern apt ocean view in heart of Panamá yoo tower
Apr 21 – 28
$170 per night
Superhost
Cabin in Panamá Oeste
Cabaña Mirador by Casa Amaya
Mar 29 – Apr 5
$60 per night
Guest favorite
Apartment in Juan Gallego
Pebos Reef, apt #1, Amazing location !
Jul 9 – 16
$170 per night
Guest favorite
Guesthouse in Torio
Torio guesthouse with panoramic view
Jun 6 – 13
$67 per night
Superhost
Farm stay in Santa Fe
Santa Fe villa with a espectacular view
Oct 14 – 21
$75 per night
Guest favorite
Farm stay in Bajo Boquete
Casitas in Butterfly and Honey Farm
Aug 9 – 16
$129 per night
Guest favorite
Loft in Panamá
Loft Studio | By Paradox
Feb 16 – 23
$59 per night
Guest favorite
Cabin in Torio
Cozy open space, unique jungle views, river access
Jan 24 – 31
$102 per night
Superhost
Villa in Bocas del Toro
Bocas del toro - Villa over the water- Bahia Coral
Jan 29 – Feb 5
$389 per night

Your guide to Panama

All About Panama

A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.

The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.


The best time to stay in a vacation rental in Panama

The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.

Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.


Top things to do in Panama

Casco Viejo

As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.

Panama Canal

When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.

Bocas Del Toro

Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.

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