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Saint Charles vacation rentals

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Top-rated vacation rentals in Saint Charles

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Rental unit in Saint Charles
Stay on Main!
Stay on Main! Cozy studio apartment directly on Main Street in St. Charles MO. Studio that has a staircase directly to the north end of Main Street, you can be on Main along the shops and restaurants in seconds. Unit has street parking only, and the staircase is shared with another short term rental that I also operate. Free wifi, coffee. There is a full bathroom, kitchen space and a king bed. Unit is brand new, it can be noisy on weekend evenings from the street.
$105 per night
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Rental unit in Saint Charles
South Main Comfort
Check out this very stylish 1 bedroom apartment on South Main. All of the amenities have been checked off the list from a dedicated office space and good sized living room, to an outdoor (shared) dinning area, historic styling in modern comforts. King bed, laundry in unit, dishwasher, and free 24/7 gym access down the street along with off street parking. We've thought of it all to help you be more comfortable for your stay in St. Charles!
$126 per night
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Rental unit in Saint Charles
Main Street Living! 2 Bedroom Unit right On Main!
Come enjoy Main Street Living Right on Main Street, directly above a Wine Cafe in the original Customs House in St. Charles, MO. You'll love the beautiful updates and amenities in this charming and historic property. Large enough for 6 adults to sleep comfortably, and two separated bedrooms. Very central in location on Main Street, with plenty of shopping and dining all in walking distance.
$173 per night
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Stay near Saint Charles's top sights

Photo of Ameristar Casino Resort Spa St. Charles
Ameristar Casino Resort Spa St. Charles42 locals recommend
Photo of The Family Arena
The Family Arena12 locals recommend
Photo of Hollywood Casino St. Louis
Hollywood Casino St. Louis20 locals recommend
Photo of St. Charles Convention Center
St. Charles Convention Center6 locals recommend
Photo of Tucanos Brazilian Grill
Tucanos Brazilian Grill8 locals recommend
Photo of Bar Louie - Streets of St. Charles
Bar Louie - Streets of St. Charles21 locals recommend

Other great vacation rentals in Saint Charles

Rental unit in Saint Charles
Pop Lucks Guest Suite Steps From Historic Main St
$111 per night
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Rental unit in Saint Charles
The Bricks On Main-King Bed on Historic Main St.
$92 per night
Rental unit in Saint Charles
Ella Rose Guest Suite in Historic Old St Charles
$108 per night
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Home in Saint Charles
Historic 5th Street House - Fully Rehabbed # 1
$114 per night
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Rental unit in Saint Charles
2 Bedroom, 1 Bath Apartment, Short Walk to Main!
$138 per night
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Home in Saint Charles
Bright & Cozy Shotgun 1 Block from Historic DT.
$120 per night
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Hotel room in Saint Charles
1st Capital Mansion Boutique Hotel - Suite 302
$109 per night
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Bungalow in Saint Charles
Patio House, secluded in heartbeat of Main Street
$127 per night
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Cottage in Saint Charles
The Rose Cottage -a short walk to Historic Main St
$135 per night
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Hotel room in Saint Charles
1st Capitol Mansion Boutique Hotel - Suite 201
$100 per night
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Rental unit in Saint Charles
River View - 2 bed, 1 bath on Main Street
$155 per night
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Rental unit in Saint Charles
2 bedroom apartment with a balcony near Main St!
$143 per night
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