Private suite vacation rentals in South Carolina

Find and book unique private suite rentals on Airbnb

Top-rated private suite rentals in South Carolina

Guests agree: these private suite rentals are highly rated for location, cleanliness, and more.

Guest favorite
Guest suite in Hilton Head Island
LOCATION! Harbour, Dining, Shops, Beach-1.4 mile
Location .. Location .. Location !!! Private guest suite with independent entrance from outside, total privacy, and complete amenities, queen bed and full bath (no kitchen). Just step outside - great water-front restaurants with live music, weekly fireworks during summer, bars, shops, outdoor pool and BBQ. Supermarkets and more restaurants in 10 minutes walking. Free shuttle from April till September, beach only 1.4 miles. Great golfing, biking, tennis, fishing and water sports.
Oct 12 – 19
$93 per night
4.95 out of 5 average rating, 268 reviews
Guest favorite
Guest suite in Charleston
Spend the Night in a Photographer's Studio!
This bright and clean mid century modern style bedroom is a great retreat for couples, solo, and business travelers. Some features include dual shower heads, private washer & dryer and cozy seating area. Only 12 minutes to the airport and 4 minutes to I-526, the location is considered “centrally located.” 7 miles from downtown Charleston. 14 miles to Folly Beach. Close to many of the most popular wedding venues, plantations, and all the secret places the LowCountry has to offer.
Sep 4 – 11
$89 per night
4.89 out of 5 average rating, 369 reviews
Guest favorite
Guest suite in Columbia
Las Flores Private suite in Columbia SC
Great spacious and Private cozy space. This private suite is the best for Travellers because the space is located in a very good rest spot for I 77 and I 20 . Also great for remote work or sort vacation to Columbia SC. This place locate in North East Columbia, 7 minutes to Fort Jackson military base [Amenities ] refrigerator, coffeemaker, Microwave, Smart tv, couch, dining table, and of course a king size bed The neighborhood is very clean, peaceful, quiet and safe
Jun 27 – Jul 4
$49 per night
4.91 out of 5 average rating, 203 reviews

Popular amenities for South Carolina private suite rentals

Family-friendly private suite rentals

Guest favorite
Guest suite in Charleston
Private Riverland Loft
Aug 4 – 11
$99 per night
4.99 out of 5 average rating, 694 reviews
Guest favorite
Guest suite in Greenwood
Private Studio-Pet Friendly. 6 min to hospital
May 13 – 20
$48 per night
4.94 out of 5 average rating, 126 reviews
Guest favorite
Guest suite in James Island
Private Studio - minutes to Folly Beach & Downtown
$86 per night
4.92 out of 5 average rating, 410 reviews
Guest favorite
Guest suite in Mount Pleasant
Cathy’s Conch House. Pets welcome
Dec 20 – 27
$112 per night
4.89 out of 5 average rating, 298 reviews
Guest favorite
Guest suite in Columbia
Private Studio Apartment
Apr 22 – 29
$66 per night
4.99 out of 5 average rating, 928 reviews
Guest favorite
Guest suite in Charleston
Newly Renovated Guest Suite with Exterior Entrance
Jul 9 – 16
$124 per night
4.94 out of 5 average rating, 994 reviews
Guest favorite
Guest suite in North Charleston
Coastal Studio - Close to Beach & Downtown
Sep 16 – 23
$73 per night
4.9 out of 5 average rating, 449 reviews
Guest favorite
Guest suite in Columbia
Amazing Downtown Apartment
May 17 – 24
$88 per night
4.94 out of 5 average rating, 677 reviews
Guest favorite
Guest suite in Charleston
Quite Private Location with Free EV Charging
May 25 – Jun 1
$141 per night
4.9 out of 5 average rating, 327 reviews
Guest favorite
Guest suite in Charleston
Coastal Getaway-10 mins from DT -Marsh/Water Views
Aug 18 – 25
$153 per night
4.87 out of 5 average rating, 203 reviews
Guest favorite
Guest suite in Charleston
The Cottage On James Island
Nov 21 – 28
$121 per night
4.99 out of 5 average rating, 251 reviews
Guest favorite
Guest suite in Beaufort
Shady Rest #1 near historic downtown Beaufort
Feb 17 – 24
$104 per night
4.96 out of 5 average rating, 499 reviews

Private suite rentals with a patio

Guest favorite
Guest suite in Greenville
modern lux lakefront suite, 6mi dt GVL
Jan 27 – Feb 3
$198 per night
4.92 out of 5 average rating, 198 reviews
Guest favorite
Guest suite in Columbia
Sanctuary Suite in Spacious Bungalow
Mar 3 – 10
$83 per night
4.85 out of 5 average rating, 130 reviews
Guest favorite
Guest suite in Georgetown
“Corner of Broad” in the historic district
Nov 10 – 17
$183 per night
4.98 out of 5 average rating, 105 reviews
Guest favorite
Guest suite in Lexington
Quiet and secluded, with a lovely view
Jun 17 – 24
$86 per night
4.98 out of 5 average rating, 111 reviews
Guest favorite
Guest suite in Mount Pleasant
CaptainsQuarters843, Best location in Mt Pleasant!
May 6 – 13
$167 per night
4.99 out of 5 average rating, 152 reviews
Guest favorite
Guest suite in Chapin
Beautiful Studio Apartment on Lake Murray SC
Oct 29 – Nov 5
$89 per night
4.96 out of 5 average rating, 79 reviews
Superhost
Guest suite in Spartanburg
LAKE LOVE quaint 1 bedroom, private entrance
Jul 8 – 15
$51 per night
4.79 out of 5 average rating, 56 reviews
Guest favorite
Guest suite in Chapin
Private suite on Lake Murray. Wheelchair access.
Mar 5 – 12
$96 per night
5.0 out of 5 average rating, 23 reviews
Guest favorite
Guest suite in Moncks Corner
Peaceful Pimlico Paradise by the River
Dec 11 – 18
$92 per night
4.93 out of 5 average rating, 44 reviews
Guest favorite
Guest suite in Seneca
Forest Hills Hideaway
Mar 14 – 21
$63 per night
4.92 out of 5 average rating, 52 reviews
Guest favorite
Guest suite in Pawleys Island
Pawleys Paradise
Jun 29 – Jul 6
$97 per night
4.95 out of 5 average rating, 73 reviews
Guest favorite
Guest suite in Charleston
Cozy natural retreat with a private entrance!
Dec 11 – 18
$70 per night
4.96 out of 5 average rating, 23 reviews

Private suite rentals with a washer and dryer

Guest favorite
Guest suite in Pawleys Island
Peaceful Pawleys Plantation Getaway
Oct 19 – 26
$95 per night
4.99 out of 5 average rating, 111 reviews
Guest favorite
Guest suite in Columbia
Farmhouse Chic in the City
Sep 10 – 17
$66 per night
4.94 out of 5 average rating, 115 reviews
Guest favorite
Guest suite in Mount Pleasant
*Fully*Renovated*1bed/1baClosetoDowntown/Beach
Feb 8 – 15
$127 per night
4.91 out of 5 average rating, 291 reviews
Guest favorite
Guest suite in Charleston
Dozen Oaks on the Marsh
May 19 – 26
$138 per night
4.98 out of 5 average rating, 120 reviews
Guest favorite
Guest suite in Summerville
Flowertown Suite in Historic Downtown Summerville
Aug 7 – 14
$93 per night
4.94 out of 5 average rating, 281 reviews
Guest favorite
Guest suite in Mount Pleasant
CasitaAmore*Beach7min*Downtown10min*HypoDogs*
Apr 27 – May 4
$180 per night
5.0 out of 5 average rating, 214 reviews
Guest favorite
Guest suite in Charleston
The House of Coastal Blues | Central to Everything
Apr 26 – May 3
$169 per night
4.95 out of 5 average rating, 210 reviews
Guest favorite
Guest suite in Clinton
College View Cottage & Saltwater Pool
Sep 17 – 24
$89 per night
4.99 out of 5 average rating, 188 reviews
Guest favorite
Guest suite in Greenville
Cozy, Cute & Clean Cottage on Saluda Lake
Apr 29 – May 6
$100 per night
5.0 out of 5 average rating, 163 reviews
Guest favorite
Guest suite in Taylors
Beautiful Studio, approx. 6-7 miles to Downtown.
Jun 2 – 9
$61 per night
4.86 out of 5 average rating, 149 reviews
Superhost
Guest suite in Charleston
Guesthouse Between Folly Beach & Downtown Chas!
Aug 19 – 26
$103 per night
4.87 out of 5 average rating, 387 reviews
Guest favorite
Guest suite in Taylors
RIVER PARK COTTAGE*CHARMING, PEACEFUL & PRIVATE
Jan 21 – 28
$91 per night
4.96 out of 5 average rating, 255 reviews

Destinations to explore