Hotel vacation rentals in Eastern Antioquia
Find and book unique hotel rentals on Airbnb
Top-rated hotel rentals in Eastern Antioquia
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Eastern Antioquia hotel rentals
Family-friendly hotel rentals
Nature lodge in San Rafael
4.91 out of 5 average rating, 34 reviewsChoiba Ritmo del Rio EcoLodge Cabin and Restaurant
Jan 17 – 24
Boutique hotel in Guarne
4.65 out of 5 average rating, 17 reviewsBeautiful boutique hotel with cabin style
Feb 1 – 8
Boutique hotel in Medellín
4.67 out of 5 average rating, 12 reviews61Prado Hotel/ Junior Suite
Sep 12 – 19
Hostel in Medellín
4.55 out of 5 average rating, 96 reviewsQuadruple Room + Bathroom + Breakfast in Poblado
Dec 17 – 24
Hotel in Medellín
4.83 out of 5 average rating, 6 reviewsNice standard double room.
Jun 10 – 17
Nature lodge in Peñol
4.75 out of 5 average rating, 8 reviewsPrivate Estate with Dam, Boat & Paddle Board
Mar 23 – 30
Nature lodge in Rionegro
4.38 out of 5 average rating, 8 reviewsLA PONDEROSA HOTEL FARM
Dec 7 – 14
Hotel in San Rafael
4.1 out of 5 average rating, 10 reviewsGran Hotel San Rafael
Feb 19 – 26
Hotel rentals with a pool
Hotel room in Rionegro
4.76 out of 5 average rating, 17 reviewsMG Hotel & Suit Ciprés
Apr 17 – 24
Casa particular in Medellín
4.9 out of 5 average rating, 30 reviewsBeautiful Apartment in Medellín Center - Wide
Jun 1 – 8
Casa particular in El Peñol
New place to stayAquavilla
Sep 8 – 15
Hotel room in Medellín
4.84 out of 5 average rating, 70 reviewsClass El Poblado Medellin Family&Business 360°view
Apr 15 – 22
Hotel room in Medellín
4.68 out of 5 average rating, 34 reviews3Bedroom apartment with private pool and breakfast
Jan 5 – 12
Hotel room in Medellín
4.56 out of 5 average rating, 9 reviewsPresidencial (Breakfast included/Daily cleaning)
Aug 1 – 8
Hotel room in Medellín
4.89 out of 5 average rating, 9 reviewsCiudad del Rio Poblado, the most vibrant area, x7
Aug 20 – 27
Hotel room in Barbosa
4.82 out of 5 average rating, 11 reviewsCasa Finca between mountains, with jacuzzi and waterfalls
Jul 1 – 8
Hotel rentals with a patio
Casa particular in Medellín
4.97 out of 5 average rating, 66 reviewsEnjoy the best location
Sep 27 – Oct 4
Casa particular in Medellín
5.0 out of 5 average rating, 6 reviewsLa Montaña Campesina
Aug 5 – 12
Hotel room in Guarne
5.0 out of 5 average rating, 7 reviewsEcolodge in the East of Antioquian
Jun 3 – 10
Casa particular in Guarne
4.8 out of 5 average rating, 20 reviewsLuxury Estate with Fireplace and Jacuzzi
Jun 25 – Jul 2
Hotel room in Medellín
4.78 out of 5 average rating, 18 reviewsChic loft in Laureles
Jun 21 – 28
Nature lodge in La Unión
5.0 out of 5 average rating, 6 reviewsGlamping Montecielo - Cabña "Monte Sol"
Mar 17 – 24
Hotel in Medellín
4.84 out of 5 average rating, 77 reviewsLuxury with balcony and king bed
Sep 26 – Oct 3
Boutique hotel in Guatapé
4.88 out of 5 average rating, 57 reviewsdigital nomad room + views rock lake village birds
Oct 8 – 15
Destinations to explore
- Pereira Vacation rentals
- Guatapé Vacation rentals
- La Vega Vacation rentals
- Santa Elena Vacation rentals
- Rionegro Vacation rentals
- Envigado Vacation rentals
- Santa Fe de Antioquia Vacation rentals
- SANTAGUEDA Vacation rentals
- Llano Grande Vacation rentals
- Cali Vacation rentals
- Bogotá Vacation rentals
- Medellín Vacation rentals
- Boutique hotel rentals Colombia
- Hotel rentals Colombia
- Aparthotel rentals Colombia
- Hotel rentals Medellín
- Boutique hotel rentals Medellín
- Hotel rentals El Poblado
- Boutique hotel rentals El Poblado
- Hotel rentals Antioquia
- Boutique hotel rentals Antioquia
- Rentals with an accessible height bed Eastern Antioquia
- Family-friendly rentals Eastern Antioquia
- Rentals with lake access Eastern Antioquia
- Rentals with pools Eastern Antioquia
- Kid-friendly rentals Eastern Antioquia
- Rentals with outdoor seating Eastern Antioquia
- Villa rentals Eastern Antioquia
- Waterfront rentals Eastern Antioquia
- Rentals with a kayak Eastern Antioquia
- Loft rentals Eastern Antioquia
- Rentals with a patio Eastern Antioquia
- Fitness-friendly rentals Eastern Antioquia
- Nature eco lodge rentals Eastern Antioquia
- Pet-friendly rentals Eastern Antioquia
- Rentals with breakfast Eastern Antioquia
- Boutique hotel rentals Eastern Antioquia
- Farmstay rentals Eastern Antioquia
- Hostel rentals Eastern Antioquia
- Serviced apartment rentals Eastern Antioquia
- Rentals with a fireplace Eastern Antioquia
- Tiny house rentals Eastern Antioquia
- Apartment rentals Eastern Antioquia
- Wheelchair accessible rentals Eastern Antioquia
- Rentals with a washer and dryer Eastern Antioquia
- Cabin rentals Eastern Antioquia
- House rentals Eastern Antioquia
- Rentals with beach access Eastern Antioquia
- Condo rentals Eastern Antioquia
- Monthly Rentals Eastern Antioquia
- Rentals with a hot tub Eastern Antioquia
- Cottage rentals Eastern Antioquia
- Smoking-friendly rentals Eastern Antioquia
- Beachfront rentals Eastern Antioquia
- Rentals with a home theater Eastern Antioquia
- Rentals with an EV charger Eastern Antioquia
- Rentals with a sauna Eastern Antioquia
- Rentals with a fire pit Eastern Antioquia
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes