Hotel vacation rentals in Lee County
Find and book unique hotel rentals on Airbnb
Top-rated hotel rentals in Lee County
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Lee County hotel rentals
Family-friendly hotel rentals
Hotel in Bonita Springs
4.53 out of 5 average rating, 126 reviewsBonita Beach Inn & Suites Two Double Beds 201
Mar 12 – 19
Hotel in Bonita Springs
4.54 out of 5 average rating, 182 reviewsBonita Beach Inn & Suites Two Double Beds 202
Sep 8 – 15
Hotel in Bonita Springs
4.57 out of 5 average rating, 123 reviewsBonita Beach Inn & Suites Queen 205
Feb 18 – 25
Hotel in Bonita Springs
4.41 out of 5 average rating, 86 reviewsBonita Beach Inn & Suites Queen 101
Jun 22 – 29
Hotel in Bonita Springs
4.45 out of 5 average rating, 77 reviewsBonita Beach Inn & Suites Two Double Beds 204
Mar 10 – 17
Hotel in Bonita Springs
4.41 out of 5 average rating, 102 reviewsBonita Beach Inn & Suites Queen 105
Feb 10 – 17
Hotel in Bonita Springs
4.42 out of 5 average rating, 188 reviewsBonita Beach Inn & Suites Two Double Beds 206
Sep 24 – Oct 1
Hotel in Bonita Springs
4.44 out of 5 average rating, 165 reviewsBonita Beach Inn & Suites 103
Feb 28 – Mar 7
Hotel rentals with a pool
Hotel room in Bonita Springs
New place to stayBeachside Bliss: Spacious Suites w/ Full Kitchen
Nov 22 – 29
Hotel in Cape Coral
New place to stayCasa Loma Motel Cape Coral King Bed
Mar 6 – 13
Resort in Sanibel
Sanibel Cottages Resort - 2 Bedroom Condo
Apr 14 – 21
Resort in Sanibel
Shell Island Beach Resort - 2 Bedroom
Apr 14 – 21
Room in Fort Myers Beach
Diamond Head, Beach Front, Sat-Sat rental.
Jun 17 – 24
Resort in Captiva
Plantation Beach - 2 Bedroom Condo
Feb 28 – Mar 7
Resort in Captiva
South Seas And South Seas Island - 2 Bedroom
Jan 3 – 10
Boutique hotel in Fort Myers Beach
4.73 out of 5 average rating, 94 reviewsLatitude 26 Waterfront Resort Marina - King Studio
Oct 12 – 19
Hotel rentals with a patio
Resort in Estero
Charming Studio Villa at Hyatt Coconut Cove!
Nov 18 – 25
Hotel in Saint James City
4.83 out of 5 average rating, 6 reviewsKing Suite with Bedroom, Kitchen, & View
Mar 12 – 19
Hotel in Saint James City
King Efficiency with Living Room & Kitchen
Dec 16 – 23
Boutique hotel in Fort Myers Beach
4.67 out of 5 average rating, 3 reviewsLatitude 26 Ft Myers Beach- Waterfront King Studio
Jun 14 – 21
Boutique hotel in Fort Myers Beach
4.91 out of 5 average rating, 11 reviewsLatitude 26 Resort - King/Queen Suite w/Kitchen
Jun 20 – 27
Resort in Fort Myers Beach
New place to stayPartial Ocean/Pool view Balcony resort suit
Mar 11 – 18
Boutique hotel in Fort Myers Beach
Latitude 26 Resort & Marina - 2 Queen Studio - ADA
Jan 28 – Feb 4
Boutique hotel in Fort Myers Beach
Latitude 26 Resort & Marina- King /Queen Bed Suite
Feb 21 – 28
Destinations to explore
- Aparthotel rentals United States
- Hotel rentals United States
- Boutique hotel rentals United States
- Boutique hotel rentals Florida
- Hotel rentals Florida
- Aparthotel rentals Florida
- Boutique hotel rentals Florida
- Hotel rentals Florida
- Aparthotel rentals Florida
- Hotel rentals Tampa
- Hotel rentals Naples
- Rentals with a kayak Lee County
- Condo rentals Lee County
- Monthly Rentals Lee County
- Rentals with an EV charger Lee County
- Rentals with beach access Lee County
- Townhouse rentals Lee County
- Rentals with a hot tub Lee County
- Kid-friendly rentals Lee County
- Rentals with outdoor seating Lee County
- Rentals with a patio Lee County
- House rentals Lee County
- Apartment rentals Lee County
- Rentals with pools Lee County
- Rentals with a fireplace Lee County
- Rentals with a fire pit Lee County
- Rentals with breakfast Lee County
- Rentals with lake access Lee County
- Rentals with an accessible height toilet Lee County
- Private suite rentals Lee County
- Villa rentals Lee County
- Beachfront rentals Lee County
- Smoking-friendly rentals Lee County
- Tiny house rentals Lee County
- Cottage rentals Lee County
- Waterfront rentals Lee County
- Bungalow rentals Lee County
- Fitness-friendly rentals Lee County
- Family-friendly rentals Lee County
- Rentals with a washer and dryer Lee County
- Pet-friendly rentals Lee County
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes