Guesthouse vacation rentals in Missouri
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Top-rated guesthouse rentals in Missouri
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Missouri guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Birch Tree
4.78 out of 5 average rating, 174 reviewsCollier Cabin in Pine Hollow ~ Eminence, MO
Aug 3 – 10
Guesthouse in Marthasville
4.96 out of 5 average rating, 224 reviewsHazel's House by the Katy Trail
Oct 28 – Nov 4
Guesthouse in Salem
4.81 out of 5 average rating, 315 reviewsCourtesy Curve Traveler's Rest
Nov 13 – 20
Guesthouse in Columbia
4.95 out of 5 average rating, 205 reviewsNature guesthouse by the A frame Studio
Apr 1 – 8
Guesthouse in Kansas City
4.98 out of 5 average rating, 114 reviewsNorthfield Village Private Apartment
Jun 2 – 9
Guesthouse in Hermann
4.99 out of 5 average rating, 115 reviewsGrapevine Guesthouse
Jul 2 – 9
Guesthouse in St. Louis
4.89 out of 5 average rating, 855 reviewsUnique Carriage House: Fun for the whole family!
May 24 – 31
Guesthouse in Carl Junction
4.64 out of 5 average rating, 139 reviewsYear-Round 100° Heated Pool with Lakefront Views
Feb 11 – 18
Guest house rentals with a patio
Guesthouse in Branson
4.82 out of 5 average rating, 116 reviewsLavender Paradise: Room #26 at The Bradford
Sep 21 – 28
Guesthouse in Independence
4.89 out of 5 average rating, 72 reviewsAdorable one bedroom Guesthouse in the woods.
Nov 3 – 10
Guesthouse in Joplin
4.99 out of 5 average rating, 100 reviewsMike & Angie’s Private-Cozy furnished Guest House
Sep 26 – Oct 3
Guesthouse in Blue Eye
5.0 out of 5 average rating, 69 reviewsTurtle Cove- Hot tub, Paddle brds, Kayaks Included
Nov 25 – Dec 2
Guesthouse in Rocheport
5.0 out of 5 average rating, 59 reviewsJust off the beaten path
Jul 12 – 17
Guesthouse in Poplar Bluff
5.0 out of 5 average rating, 12 reviewsCozy Apartment Glamping w/ pond and forest access!
Jul 16 – 23
Guesthouse in Farmington
5.0 out of 5 average rating, 31 reviewsThe Dove's Nest established July 2023
Sep 18 – 25
Guesthouse in Branson
4.91 out of 5 average rating, 56 reviewsLuxe Mid-Century Mod Home
Apr 28 – May 5
Guest house rentals with a washer and dryer
Guesthouse in Webb City
4.96 out of 5 average rating, 403 reviewsBright and Modern Private Guesthouse near Route 66
Sep 17 – 24
Guesthouse in Fordland
4.77 out of 5 average rating, 119 reviewsMagnolia TINY HOUSE at Promised Land Farm
Mar 31 – Apr 7
Guesthouse in Ash Grove
4.94 out of 5 average rating, 110 reviewsGRAND REOPENING Ash Grove home with a Zen feel
Aug 12 – 19
Guesthouse in Kansas City
4.96 out of 5 average rating, 137 reviewsPine Hill Farm
Oct 28 – Nov 4
Guesthouse in St. James
4.92 out of 5 average rating, 156 reviewsSAVE, MO Cottage
Jul 21 – 28
Guesthouse in St. Louis
4.8 out of 5 average rating, 206 reviewsGothic Revival 1896 Carriage Cottage
Jun 29 – Jul 6
Guesthouse in Barnard
4.97 out of 5 average rating, 65 reviewsRed Rock Loft - Pet Friendly in Beautiful Setting
Oct 28 – Nov 4
Guesthouse in Kirksville
5.0 out of 5 average rating, 31 reviewsEvergreen Cabin in Country Setting!
Oct 17 – 24
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