Guesthouse vacation rentals in Orange County
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Top-rated guesthouse rentals in Orange County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Orange County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Cary
4.92 out of 5 average rating, 295 reviewsCentral to Everything, Renovated, Dog Friendly.
Sep 22 – 29
Guesthouse in Apex
4.92 out of 5 average rating, 347 reviewsCountry place close to all Triangle locations
Jul 23 – 30
Guesthouse in Chapel Hill
4.96 out of 5 average rating, 340 reviewsCozy Secluded Accessible West Wing
Jul 1 – 8
Guesthouse in Durham
4.99 out of 5 average rating, 229 reviewsLaCasita, charming 2-story guest house near Duke
Jan 26 – Feb 2
Guesthouse in Saxapahaw
4.92 out of 5 average rating, 699 reviewsThe Yurt at Frog Pond Farm
Jun 26 – Jul 3
Guesthouse in Durham
4.87 out of 5 average rating, 181 reviewsRockwood Oasis Studio BR Bath no kitchen
Oct 8 – 15
Guesthouse in Chapel Hill
Serenity Room 12 min. from UNC
Jul 23 – 30
Guest house rentals with a patio
Guesthouse in Durham
4.95 out of 5 average rating, 118 reviewsSpotless Scent & Mold-Free Guesthouse Near Duke!
Oct 7 – 14
Guesthouse in Fuquay-Varina
5.0 out of 5 average rating, 45 reviewsSunset Studio near Downtown Fuquay, no chores!
Aug 1 – 8
Guesthouse in Mebane
4.92 out of 5 average rating, 25 reviewsMebane Guest House
Jul 24 – 31
Guesthouse in Leasburg
4.82 out of 5 average rating, 22 reviewsNEW! Hyco Lake Gem w/ game room
Aug 26 – Sep 2
Guesthouse in Durham
5.0 out of 5 average rating, 8 reviewsNew Apt- walk to everything Rockwood
Sep 5 – 12
Guesthouse in Durham
4.98 out of 5 average rating, 85 reviewsGreat Studio Suite with exclusive hot tub & pool!
Mar 24 – 31
Guesthouse in Durham
5.0 out of 5 average rating, 19 reviews“Meelie Doll”~ Private - Cozy Stdio Apt abv garage
Jul 29 – Aug 5
Guesthouse in Chapel Hill
4.81 out of 5 average rating, 31 reviewsGuesthouse + Access to Morgan Creek Trail
Mar 1 – 8
Guest house rentals with a washer and dryer
Guesthouse in Cary
5.0 out of 5 average rating, 112 reviewsGuest House on the Cary Downtown Park!
Jun 26 – Jul 3
Guesthouse in Durham
5.0 out of 5 average rating, 49 reviewsDelightfully Durham: Guesthouse with Kitchen!
Jun 14 – 21
Guesthouse in Pittsboro
4.95 out of 5 average rating, 22 reviewsThe Sacred Cedar
Jul 26 – Aug 2
Guesthouse in Durham
4.9 out of 5 average rating, 63 reviewsDuke Park Carriage house - Studio
Jul 15 – 22
Guesthouse in Durham
5.0 out of 5 average rating, 5 reviewsPinky - A Cute Durham Camping Trailer
Sep 10 – 17
Guesthouse in Durham
4.93 out of 5 average rating, 89 reviewsAdorable + private guesthouse close to downtown
Aug 3 – 10
Guesthouse in Durham
4.93 out of 5 average rating, 41 reviewsDuplex filled with natural light
Oct 3 – 10
Guesthouse in Apex
4.83 out of 5 average rating, 6 reviewsThe Carriage House | A private guest studio
Sep 18 – 25
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