Villa vacation rentals in Isle of Palms
Find and book unique villas on Airbnb
Top-rated villa rentals in Isle of Palms
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Isle of Palms villa rentals
Villa rentals with a pool
Villa in Seabrook Island
5.0 out of 5 average rating, 12 reviewsClose to beach, pools,golf & tennis+Amenity Card*
Oct 27 – Nov 3
Villa in Saint Helena Island
4.99 out of 5 average rating, 69 reviewsLittle Palm Villa | Oceanfront
Jan 24 – 31
Villa in Saint Helena Island
4.99 out of 5 average rating, 78 reviewsSandy Toes Condos
Mar 5 – 12
Villa in Seabrook Island
4.91 out of 5 average rating, 11 reviewsLuxury Seabrook Isl Beach Condo
Dec 4 – 11
Villa in Seabrook Island
4.83 out of 5 average rating, 59 reviewsPrivate island villa with luxury resort amenities!
Oct 15 – 22
Villa in Seabrook Island
4.9 out of 5 average rating, 31 reviewsUpscale Villa, Amenity Included! Dog Friendly
Jun 7 – 14
Villa in Seabrook Island
4.85 out of 5 average rating, 33 reviewsSeabrook Golf View Villa: Pickleball, Pool & Bike
Aug 4 – 11
Villa in Seabrook Island
4.97 out of 5 average rating, 59 reviewsBeautiful and Spacious 2 Bedroom Courtside Villa!
Nov 23 – 30
Private villa rentals
Villa in Kiawah Island
4.96 out of 5 average rating, 98 reviewsSpacious new 2BR Villa across beach near Sanctuary
Apr 2 – 9
Villa in Edisto Island
4.73 out of 5 average rating, 52 reviewsLoft-e-Lagoon *No Cleaning Fee*
Jan 13 – 20
Villa in Kiawah Island
4.97 out of 5 average rating, 88 reviewsLagoon view villa with office, easy walk to beach!
Mar 5 – 12
Villa in Kiawah Island
4.93 out of 5 average rating, 96 reviewsClean & Comfortable! Steps to the beach!
May 13 – 20
Villa in Edisto Island
4.97 out of 5 average rating, 36 reviewsRelax in a Happy Place
May 15 – 22
Villa in Seabrook Island
4.86 out of 5 average rating, 51 reviews711 Spinnaker centrally located to EVERYTHING!
Nov 1 – 8
Villa in Isle of Palms
4.76 out of 5 average rating, 46 reviewsUpdated 2BR | Balcony | Pool | Dock
Aug 31 – Sep 7
Villa in Isle Of Palms
4.78 out of 5 average rating, 37 reviews7C Seagrove - Sweetgrass
Mar 29 – Apr 5
Luxury villa rentals
Villa in Kiawah Island
5.0 out of 5 average rating, 26 reviewsOcean Front! Beach is steps away. Clean and Crisp!
Mar 23 – 30
Villa in Kiawah Island
5.0 out of 5 average rating, 3 reviewsIncredible, completely renovated oceanfront villa
Sep 30 – Oct 7
Villa in Sullivan's Island
4.57 out of 5 average rating, 21 reviewsHaven by AvantStay | Luxury Beachfront Retreat
Feb 14 – 21
Villa in Kiawah Island
5.0 out of 5 average rating, 15 reviewsOceanfront Windswept Villa
Aug 23 – 30
Villa in Isle of Palms
5.0 out of 5 average rating, 4 reviewsOceanfront Villa in Wild Dunes! Community Pool!
Oct 25 – Nov 1
Villa in Kiawah Island
4.89 out of 5 average rating, 18 reviewsSpacious Penthouse 3BR 3Bath Villa with Ocean View
Jan 10 – 17
Villa in Kiawah Island
4.94 out of 5 average rating, 52 reviewsOpen floor plan 2 Bedroom Turtle Cove Villa
Dec 19 – 26
Villa in Seabrook Island
Popular Spinnaker! Close to Beach!
Mar 30 – Apr 6
Quick stats about villa rentals in Isle of Palms
Total rentals
70 properties
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Rentals with a pool
70 properties have a pool
Family-friendly rentals
60 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
$170 before taxes and fees
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- Monthly Rentals Isle of Palms
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