Vacation rentals in Medicine Park

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Top-rated vacation rentals in Medicine Park

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite
Guesthouse in Medicine Park
Harper's Landing Waterfront Medicine Park Ft Sill
Beautiful Waterfront Guesthouse (1 BR 1 BA) nestled between the base of Mt. Scott in the Wichita National Wildlife Refuge and Gondola Lake. King Size Bed & A Queen Size Sofa Sleeper Fireplace Well stocked Kitchen Walk-In Shower Cozy Living Area Screened patio Large Screen Smart Television with Direct TV, Netflix, and other streaming options. Waterfront Fire Pit Dock with Access to Kayak, Paddle Boat, Fishing Steps to Hiking and Biking Trails Minutes to town Minutes to Ft Sill Gate (Apache)
Feb 10 – 17
$170 per night
4.98 out of 5 average rating, 275 reviews
Guest favorite
Cabin in Medicine Park
Updated Cabin w/ 360-Degree Mtn View: 1 Mi to Lake
Book your trip to Medicine Park - Oklahoma's first resort town teeming with historic charm and natural beauty! This 2-bed, 2-bath vacation rental features modern furnishings, a fully equipped kitchen, and a furnished deck overlooking spectacular Wichita Mountain views. When it's time to make a splash, visit Lake Lawtonka or Bath Lake Medicine Park just 1 mile from this cabin. If you prefer fun on land, Wichita Mountains Wildlife Refuge offers hiking, biking, fishing, wildlife viewing, and more!
Feb 11 – 18
$210 per night
4.95 out of 5 average rating, 127 reviews
Guest favorite
Cabin in Medicine Park
The Flute Player
The Flute Player cabin is in the heart of Medicine Park! Enjoy a stroll to the shops, galleries, & restaurants, or a short drive to the many activities the area has to offer. Flute Player is perfect for your weekend getaway, romantic retreat, reunions or military graduations. Some of the cottage amenities include: fully equipped kitchen, AC & heat, flat screen TV indoors and on the porch. Complimentary coffee, tea & bottled water. We offer early check ins. Message us for details.
Sep 10 – 17
$108 per night
4.93 out of 5 average rating, 279 reviews

Popular amenities for Medicine Park vacation rentals

Stay near Medicine Park's top sights

Medicine Park Aquarium and Natural Sciences Center29 locals recommend
Bath Lake Medicine Park7 locals recommend
The Old Plantation Restaurant36 locals recommend
Riverside Cafe22 locals recommend
Park Tavern9 locals recommend
Cobblestone Creamery4 locals recommend

Other great vacation rentals in Medicine Park

Guest favorite
Guesthouse in Lawton
Home with (Pool; Open May-Oct) near Post & Refuge
Sep 26 – Oct 3
$167 per night
5.0 out of 5 average rating, 192 reviews
Guest favorite
Home in Medicine Park
Cute & Cozy with Trailer Parking
Oct 25 – Nov 1
$124 per night
5.0 out of 5 average rating, 10 reviews
Guest favorite
Cabin in Medicine Park
Cheerful 2 bedroom cabin with parking on premises!
Sep 4 – 11
$109 per night
4.94 out of 5 average rating, 53 reviews
Guest favorite
Cabin in Medicine Park
Bedrock Cabin ~ Best view in Medicine Park!
Apr 16 – 23
$239 per night
5.0 out of 5 average rating, 5 reviews
Guest favorite
Cabin in Medicine Park
New Construction- Modern 3 Bedroom + Loft House!
Jun 18 – 25
$325 per night
4.95 out of 5 average rating, 77 reviews
Guest favorite
Guest suite in Medicine Park
Stardust Inn: Buffalo Spirit
Feb 5 – 12
$94 per night
4.99 out of 5 average rating, 68 reviews
Guest favorite
Cabin in Medicine Park
Eagles Nest (Hot Tub)
Apr 23 – 30
$192 per night
4.98 out of 5 average rating, 51 reviews
Guest favorite
Home in Medicine Park
Acorn Cottage: bright luxury boho home
May 1 – 8
$161 per night
5.0 out of 5 average rating, 33 reviews
Guest favorite
Cabin in Medicine Park
Isn't She Lovely Cobblestone Retreat
Sep 4 – 11
$317 per night
4.96 out of 5 average rating, 23 reviews
Superhost
Cabin in Medicine Park
Sunflower Cottage
Apr 8 – 15
$225 per night
4.95 out of 5 average rating, 19 reviews
Guest favorite
Home in Lawton
Cobblestone by the Park
Aug 16 – 23
$162 per night
4.96 out of 5 average rating, 27 reviews
Guest favorite
Cabin in Medicine Park
Mountain Boomer
Jan 24 – 31
$176 per night
5.0 out of 5 average rating, 49 reviews

Quick stats about vacation rentals in Medicine Park

Total rentals

90 properties

Rentals with dedicated workspaces

30 properties have a dedicated workspace

Pet-friendly rentals

30 properties allow pets

Family-friendly rentals

40 properties are a good fit for families

Total number of reviews

5.6K reviews

Nightly prices starting at

$50 before taxes and fees

Your guide to Medicine Park

All About Medicine Park

Located in southwestern Oklahoma, Medicine Park is a small community with significant Native American history and cobblestone architecture dating back to the early 1800s. As Oklahoma's first resort town, Medicine Park also offers an abundance of open-air activities, including boating, horseback riding, and rock climbing throughout its picturesque countryside dotted with wildlife. The community is surrounded by the rocky landscape of the imposing Wichita Mountains, encircling the northwest part of town, and there are several lakes, including the popular Bath Lake. Outside of Medicine Park, the landscape ranges from sweeping green prairies to rugged wilderness dotted with bison.

In town, multiple eateries offer local specialities such as fried onion burgers and catfish dinners, or you just indulge in an old-fashioned soda as you meander through the local shops of this scenic town. Bath Lake is a popular spot to take a dip and watch the sun set against a picturesque mountain backdrop.


The best time to stay in a vacation rental in Medicine Park

Summer is the peak season for Medicine park cabin rentals and outdoor activities, and you can join the town's annual birthday celebration in early July. Fall is beautiful as the leaves start to change colors. The Native American Festival and Art Walk happens in October, with performances by local and regional artists. Winter brings colder temperatures but offers a richer view of the starry sky and snow-covered mountain landscape. Spring is a beautiful time to visit and enjoy the wildflower blooms. Mountain bike enthusiasts flock to the April Fools Mountain Bike Festival in early April.


Top things to do in Medicine Park

Fort Sill National Historic Landmark and Museum

Located 20 minutes away from the center of Medicine Park, Fort Sill National Historic Landmark and Museum offers 144,514 square feet of military history. This is the only national memorial in Oklahoma and it also pays tribute to the soldiers and Native Americans who lived on Fort Sill during its 200-year history. Exhibits detail how leaders, activists, and celebrities have influenced America's military presence.

Southern Plains Indian Museum

Around 50 minutes from town in Anadarko, the Southern Plains Indian Museum is home to three galleries, which showcase art created by Indigenous peoples including the Wichita, Southern Cheyenne, and Kiowa. The on-site collection includes more than 5,000 artifacts including eagle feather bonnets and buffalo hide tipis, and the museum also highlights the work of contemporary craftspeople. Minutes away, the National Hall of Fame for Famous American Indians is an open-air gallery of busts of historically important Native Americans.

The Lawtonka Trails in Medicine Park

With six trails to choose from, Lawtonka Trails is a great way to explore the beautiful cobblestone landscape of Medicine Park. Situated just minutes from town, these trails wind between Lake Lawtonka and Mount Scott — offering picturesque views of boulders, rock formations, winding creeks, and the tree-covered mountain terrain. Hikers can choose from a leisurely stroll to more challenging treks, or bring a mountain bike for a refreshing ride with scenic views.

Destinations to explore