Hotel vacation rentals in Upstate South Carolina
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Top-rated hotel rentals in Upstate South Carolina
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Upstate South Carolina hotel rentals
Family-friendly hotel rentals
Hotel room in Clemson
5.0 out of 5 average rating, 7 reviewsTwo private rooms with bathroom
Jun 29 – Jul 6
Hotel room in Highlands
4.82 out of 5 average rating, 11 reviewsInn at Mill Creek Suite 4 - Satulah
Jan 26 – Feb 2
Hotel room in Tryon
4.83 out of 5 average rating, 47 reviewsGreenLife Inn at Mimosa Room 208
Jul 21 – 28
Boutique hotel in Chimney Rock
4.95 out of 5 average rating, 39 reviewsQueen Bedroom - No Cleaning Fees & Free Breakfast!
Feb 24 – Mar 3
Hotel in Hendersonville
4.67 out of 5 average rating, 6 reviewsLarge King Room, Breakfast & WIFI included
Jun 17 – 24
Hotel in Fletcher
4.86 out of 5 average rating, 56 reviewsCabin 400 sq all for you.
Feb 26 – Mar 5
Resort in Scaly Mountain
Nantahala
Jan 29 – Feb 5
Hotel room in Dillsboro
4.84 out of 5 average rating, 67 reviewsDillsboro Inn Family Suite
Jun 29 – Jul 6
Hotel rentals with a pool
Hotel room in Clarkesville
Spacious 2BD/2BA - Blue Ridge Mountains
Dec 6 – 13
Hotel room in Lake Lure
4.83 out of 5 average rating, 6 reviewsChimney Rock Inn - Room 8
Aug 5 – 12
Resort in Hendersonville
4.59 out of 5 average rating, 59 reviews304 Honeymoon Suite King Bed & Queen Sofa
Nov 20 – 27
Nature lodge in Mill Spring
4.82 out of 5 average rating, 11 reviewsBright's Creek Lodge - Double Queen w/ Balcony
Jun 3 – 10
Hotel in Greenville
5.0 out of 5 average rating, 6 reviewsWingate (K)
Aug 22 – 29
Resort in Bryson City
5.0 out of 5 average rating, 3 reviewsLodge 06 Pool View
Jan 19 – 26
Resort in Flat Rock
4.75 out of 5 average rating, 4 reviewsMill House Lodge - Studio King
Dec 3 – 10
Nature lodge in Bryson City
5.0 out of 5 average rating, 3 reviewsQuaint Airbnb village with gorgeous views!
Mar 28 – Apr 4
Hotel rentals with a patio
Hotel in Washington
4.83 out of 5 average rating, 12 reviewsThe Fitzpatrick Hotel Washington - Deluxe Rooms
Oct 22 – 29
Hotel in Whittier
4.95 out of 5 average rating, 40 reviewsThe Blue Ridge Suite at the Lodge at Smoky Cove
Jun 2 – 9
Boutique hotel in Hendersonville
4.8 out of 5 average rating, 10 reviewsDouble Queen Rm: Near DT Hendo & Flat Rock
May 24 – 31
Hotel in Lake Lure
1 Bedroom Deluxe @ Wyndham Fairfield Mountains
Jun 13 – 20
Hotel in Maggie Valley
5.0 out of 5 average rating, 13 reviewsThe Azalea Suite at the Dogwood
Jun 11 – 18
Nature lodge in Franklin
5.0 out of 5 average rating, 7 reviewsThe Lodge at Cat Creek, Appalachian Room
Jan 15 – 22
Boutique hotel in Highlands
4.83 out of 5 average rating, 6 reviewsSkyline Lodge - Hemlock King Room
Jul 4 – 11
Hotel in West Columbia
4.5 out of 5 average rating, 6 reviewsNow open 2 Bed Room
Jun 23 – 30
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