Hotel vacation rentals in South Carolina
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Top-rated hotel rentals in South Carolina
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Vacation rentals for every style
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Popular amenities for South Carolina hotel rentals
Family-friendly hotel rentals
Resort in Hilton Head Island
5.0 out of 5 average rating, 4 reviewsOceanfront, Brand new Luxury Suite!!
Apr 19 – 26
Hotel room in Edisto Island
5.0 out of 5 average rating, 12 reviewsWyndham Ocean Ridge - Edisto Island ** 1 Bedroom
Jun 6 – 13
Resort in Myrtle Beach
2 Bdrm - South Beach Resort - Myrtle Beach, SC
Dec 25 – 30
Resort in Myrtle Beach
Myrtle Beach, Ocean Front Apt, July 7- July 14
Mar 9 – 16
Hotel in Charleston
4.77 out of 5 average rating, 43 reviewsCharming Historic Inn*
Dec 13 – 20
Hotel room in Clemson
5.0 out of 5 average rating, 7 reviewsTwo private rooms with bathroom
Jun 24 – Jul 1
Resort in Myrtle Beach
5.0 out of 5 average rating, 4 reviews1 bdrm condo, South Beach Resort, Beach Access
Nov 10 – 17
Hostel in Charleston
4.72 out of 5 average rating, 380 reviewsThe Goldman Room @ The Annex
Oct 15 – 22
Hotel rentals with a pool
Hotel in Myrtle Beach
4.75 out of 5 average rating, 8 reviewsOceanfront Blvd.
Dec 24 – 31
Resort in Pawleys Island
4.55 out of 5 average rating, 11 reviewsBubbles Up at Litchfield By The Sea
Mar 9 – 16
Hotel in Myrtle Beach
4.7 out of 5 average rating, 20 reviewsOcean View Suite w. Rooftop Pool
Mar 28 – Apr 4
Resort in Myrtle Beach
5.0 out of 5 average rating, 27 reviewsAmazing Ocean views! Pool, lazy river, hot tub
May 21 – 28
Resort in Myrtle Beach
5.0 out of 5 average rating, 17 reviewsBeach Hideaway - Grande Cayman Resort MB *King bed
Feb 5 – 12
Resort in Myrtle Beach
5.0 out of 5 average rating, 20 reviewsBeachfront condo ! Beautiful ocean views.
Sep 22 – 29
Room in Irmo
5.0 out of 5 average rating, 10 reviewsRelax in beach themed room.
Jun 15 – 22
Resort in Myrtle Beach
4.75 out of 5 average rating, 72 reviewsCharming condo in Landmark hotel-Sleeps 4
Dec 14 – 21
Hotel rentals with a patio
Casa particular in Hilton Head Island
New place to stayHeritage Classic 2025 Villa
May 22 – 29
Room in Spartanburg
4.96 out of 5 average rating, 24 reviewsLovely 1 br/1 private bath.
Jun 19 – 26
Nature lodge in Greenville County
4.88 out of 5 average rating, 8 reviewsCabin near Pretty Place!
Dec 3 – 10
Resort in Myrtle Beach
4.9 out of 5 average rating, 30 reviews2bd 2ba ocean view condo
Sep 7 – 14
Boutique hotel in Sunset
4.56 out of 5 average rating, 9 reviews"Muskrat" room at Wilderness Retreat Center
Jun 2 – 9
Hotel in Hilton Head Island
5.0 out of 5 average rating, 7 reviewsCharming Hilton Head Harbor Point Resort 2bd Suite
Jul 17 – 24
Resort in Myrtle Beach
5.0 out of 5 average rating, 11 reviewsBeautiful 2 bedroom resort at Myrtle Beach
Apr 18 – 25
Hotel in Hilton Head Island
New place to stay2 BR Villa @ Barony Beach Club
Dec 13 – 20
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