Guesthouse vacation rentals in San Diego County
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Top-rated guesthouse rentals in San Diego County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in La Mesa
4.92 out of 5 average rating, 206 reviewsFig Tree Bungalow
Sep 16 – 23
Guesthouse in Chula Vista
4.95 out of 5 average rating, 476 reviewsPrivate Casita in Great Eastlake Neighborhood
Sep 29 – Oct 6
Guesthouse in Vista
4.88 out of 5 average rating, 242 reviewsPRIVATE CASITA nestled in a great neighborhood
Nov 9 – 16
Guesthouse in San Diego
4.93 out of 5 average rating, 447 reviewsPrivate Cottage in Walkable North Park w/AC
Jun 21 – 28
Guesthouse in San Diego
4.97 out of 5 average rating, 507 reviewsCentral & Serene Secret Garden Guesthouse
Sep 13 – 20
Guesthouse in San Diego
4.97 out of 5 average rating, 292 reviewsPrivate Guest House with a View
Aug 5 – 12
Guesthouse in San Diego
4.94 out of 5 average rating, 333 reviewsThe BEST NEST Clean, peaceful, private, affordable
Oct 16 – 23
Guesthouse in Oceanside
4.92 out of 5 average rating, 266 reviewsThe Sunshine House. Location, Location, Ocean.
Oct 29 – Nov 5
Guest house rentals with a patio
Guesthouse in Poway
4.99 out of 5 average rating, 117 reviews⭐️Garden studio guesthouse, resort living with pool
Guesthouse in San Diego
5.0 out of 5 average rating, 107 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Oct 25 – Nov 1
Guesthouse in San Diego
4.99 out of 5 average rating, 151 reviewsAdorable cottage in Talmadge
Mar 23 – 30
Guesthouse in Lakeside
4.94 out of 5 average rating, 100 reviewsSky Mesa-Adorable Cottage on the Hill
Jan 26 – Feb 2
Guesthouse in San Diego
4.92 out of 5 average rating, 150 reviewsCentral studio w/ private outdoor space & parking
Mar 12 – 19
Guesthouse in San Diego
4.98 out of 5 average rating, 124 reviewsPrivate Studio Cottage with Outdoor Patio
Dec 10 – 17
Guesthouse in La Mesa
4.97 out of 5 average rating, 118 reviewsSan Diego Newly Built Private Guesthouse (Sleep 5)
Oct 12 – 19
Guesthouse in San Diego
4.86 out of 5 average rating, 125 reviewsPrivate, beautiful 1-bedroom 2 story guest house
Aug 29 – Sep 5
Guest house rentals with a washer and dryer
Guesthouse in Encinitas
4.99 out of 5 average rating, 149 reviewsCoastal Farm Sanctuary Stay. 20 min to the Beach.
Aug 26 – Sep 2
Guesthouse in San Diego
4.96 out of 5 average rating, 208 reviewsPrivate beach guesthouse w/ private parking
Sep 2 – 9
Guesthouse in Encinitas
4.96 out of 5 average rating, 347 reviewsCardiff by the Sea Beach Bungalow
Sep 18 – 25
Guesthouse in San Diego
4.9 out of 5 average rating, 193 reviewsSTUNNING Casita with a View!!
Oct 21 – 28
Guesthouse in San Diego
4.95 out of 5 average rating, 108 reviewsRelax in a Centrally Located, Modern Guest House
Jan 2 – 9
Guesthouse in San Diego
4.98 out of 5 average rating, 117 reviewsCasita Hermosa - Close to everything in San Diego
Sep 20 – 27
Guesthouse in San Diego
4.91 out of 5 average rating, 114 reviewsCharming Granny Flat Near SDSU & Transit Center
Jun 8 – 15
Guesthouse in La Mesa
4.99 out of 5 average rating, 133 reviewsStunning Guest House 15 min. from Zoo, Downtown
Oct 5 – 12
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