Hotel vacation rentals in Panama
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Top-rated hotel rentals in Panama
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Panama hotel rentals
Family-friendly hotel rentals
Nature lodge in Darién Province
4.67 out of 5 average rating, 18 reviewsNo Chunga
Jul 21 – 28
Nature lodge in Cébaco
4.57 out of 5 average rating, 14 reviewsIsland Lodge Retreat Cebaco Sunrise/Cebaco Island
Mar 30 – Apr 4
Aparthotel in Alto Boquete
4.67 out of 5 average rating, 21 reviewsCabañas Villa San Miguel #1/noquete
Sep 6 – 13
Nature lodge in Isla Bastimentos
4.92 out of 5 average rating, 26 reviewsBeach Bungalow on Bastimentos w/ Meals & Transport
Feb 23 – Mar 2
Nature lodge in Santa Catalina
4.81 out of 5 average rating, 16 reviewsBeachfront - Private double bedroom
Nov 29 – Dec 6
Boutique hotel in San Carlos
4.82 out of 5 average rating, 94 reviewsB) Beach, surf and Relax with King size bed
Jul 6 – 13
Boutique hotel in Playa Morillo, Mariato
4.97 out of 5 average rating, 33 reviewsDouble room IXORA with partial ocean view balcony
Feb 16 – 23
Nature lodge in Boca del Drago
4.82 out of 5 average rating, 11 reviewsBoca del drago room ocean front
Nov 19 – 26
Hotel rentals with a pool
Boutique hotel in Panamá
4.89 out of 5 average rating, 19 reviewsPool side, Family suite, two bedroom one bath.
Apr 15 – 22
Room in Panamá
4.83 out of 5 average rating, 18 reviewsRelax Room
May 19 – 26
Hostel in Panama City
4.82 out of 5 average rating, 55 reviewsEl Puente
Jul 26 – Aug 2
Resort in Playa Coronado
4.88 out of 5 average rating, 8 reviewsPrivate suite with pool view
May 10 – 17
Hotel in Panamá
5.0 out of 5 average rating, 4 reviewsGrand International Hotel
May 10 – 17
Hotel in Panamá
4.61 out of 5 average rating, 64 reviewsComfortable room with private bathroom
Sep 19 – 26
Hotel in Playa Coronado
5.0 out of 5 average rating, 3 reviewsGolf luxury mango pool suite
Nov 18 – 25
Resort in Cañas
5.0 out of 5 average rating, 8 reviewsStandard Suite
Oct 25 – Nov 1
Hotel rentals with a patio
Casa particular in Penonomé
5.0 out of 5 average rating, 4 reviewsCozy 1 br 1 bath apartment with free parking
Jul 14 – 21
Casa particular in Río Hato
4.5 out of 5 average rating, 4 reviewsVilla en Playa Blanca Resort Río Hato
Jun 1 – 8
Casa particular in Panamá
New place to stayEntire apartment
Jul 5 – 12
Nature lodge in San Blas Islands
5.0 out of 5 average rating, 7 reviewsNatural rooms for disconnecting
Apr 24 – May 1
Resort in Boca Chica
4.67 out of 5 average rating, 9 reviewsLIVE WITH MONKEYS ON ISLA BOCA BRAVA (HAB.C.)
Jun 6 – 13
Room in Soná District
4.83 out of 5 average rating, 6 reviewsSkyRoom- Private room with shared bathroom
Mar 13 – 20
Room in Alto Boquete
4.8 out of 5 average rating, 5 reviewsLa casita de Elenita - sextuple room
Mar 6 – 13
Nature lodge in Bocas del Toro
OHANA Amazing Ocean View SURF SPOT #1
May 16 – 23
Destinations to explore
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- Family travel hub Tips and inspiration
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