House vacation rentals in Panama
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Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama house rentals
House rentals with a pool
Home in Panama
4.96 out of 5 average rating, 138 reviewsVilla Isabella in Coronado Beach Panama
Jun 25 – Jul 2
Home in contadora
4.85 out of 5 average rating, 192 reviewsvilla in counter, pearls
Sep 28 – Oct 5
Home in Panama City
4.88 out of 5 average rating, 26 reviewsBeautiful house with private pool
Aug 12 – 19
Home in Playa Mata Oscura
4.92 out of 5 average rating, 25 reviewsCasa De Ola, Jungle Beach Cabin
Apr 16 – 23
Home in Playa Venao
5.0 out of 5 average rating, 15 reviewsCasa Samambaia - sea view tropical paradise w pool
May 20 – 27
Home in San Carlos
4.93 out of 5 average rating, 87 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Oct 25 – Nov 1
Home in Playa Bluff
5.0 out of 5 average rating, 15 reviewsJungle House 100m from the beach
Apr 8 – 15
Home in Bocas Del Toro
4.96 out of 5 average rating, 90 reviewsWiona of Villa Paraiso | Beachfront Villa & Pool
Sep 6 – 13
Weekly house rentals
Home in Bocas del Toro
5.0 out of 5 average rating, 9 reviewsLa Casita Barrbra BnB
Jun 24 – Jul 1
Home in Boquete
5.0 out of 5 average rating, 12 reviewsCaturra Casita @ Finca Panda
Oct 6 – 13
Home in Santa Catalina
5.0 out of 5 average rating, 25 reviewsCasa Colibrí - modern house in the green
Jan 18 – 25
Home in Boquete
5.0 out of 5 average rating, 64 reviewsAlba Verde Guest House, Private Vacation Rental
Apr 16 – 23
Home in Corregimiento de Isla Grande
4.96 out of 5 average rating, 83 reviewsPuntita Manzanillo, fantastic sea and jungle
Mar 4 – 11
Home in El Chirú
4.91 out of 5 average rating, 11 reviewsLuxe Lagoon Villa | King Bed | Sleeps 11
Oct 15 – 22
Home in Panamá
5.0 out of 5 average rating, 6 reviewsUnique 4 room house - direct access to the beach
Feb 17 – 24
Home in Nueva California
5.0 out of 5 average rating, 10 reviewsSpacious 3 bedroom house in Volcan cloud forest
Nov 25 – Dec 2
Private house rentals
Home in Bocas del Toro
5.0 out of 5 average rating, 17 reviewsCasa del Fuego - Caribbean Beachfront Magic!
Aug 24 – 31
Home in Bajo Boquete
4.96 out of 5 average rating, 57 reviewsSpacious 3BR walking distance, close to everything
Oct 1 – 8
Home in Panamá
4.98 out of 5 average rating, 52 reviewsGolden Space | By Paradox
Sep 14 – 21
Home in Panamá
4.94 out of 5 average rating, 17 reviewsHummingbird House/Casa de Colibri
Aug 20 – 27
Home in Panamá
4.95 out of 5 average rating, 44 reviewsCozy cabin in the mountains of Cerro Azul
Jul 18 – 25
Home in Chame
4.92 out of 5 average rating, 12 reviewsEscape the city! Cozy weather and home.
May 19 – 26
Home in Boca Chicá
5.0 out of 5 average rating, 22 reviewsEntire house with private pool facing beach !
Aug 16 – 23
Home in Bastimento
4.84 out of 5 average rating, 44 reviewsBay Of The Floating Palms - Beach Front Home
Jun 10 – 17
Destinations to explore
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- Family travel hub Tips and inspiration
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