Guesthouse vacation rentals in Colleton County
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Top-rated guesthouse rentals in Colleton County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Colleton County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Beaufort
4.94 out of 5 average rating, 230 reviewsCozy private guest house
Apr 29 – May 6
Guesthouse in Beaufort
4.94 out of 5 average rating, 395 reviewsMeridian Rd. Guest House Walk to Restaurants/Parks
Sep 18 – 25
Guesthouse in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
Aug 26 – Sep 2
Guesthouse in Beaufort
4.98 out of 5 average rating, 359 reviewsThe Wren Guest House
Feb 23 – Mar 2
Guest house rentals with a patio
Guesthouse in Beaufort
4.63 out of 5 average rating, 41 reviewsWaterfront! Guest House!
Feb 27 – Mar 6
Guesthouse in Ridgeville
4.9 out of 5 average rating, 30 reviewsCute Frog
Nov 25 – Dec 2
Guesthouse in Saint George
4.96 out of 5 average rating, 55 reviewsSimmons Sweet Suite
Apr 15 – 22
Guesthouse in Seabrook
5.0 out of 5 average rating, 45 reviewsAdorable guesthouse outside Beaufort
May 22 – 29
Guesthouse in Summerville
4.98 out of 5 average rating, 52 reviewsHearts & Dreams Peaceful Family Retreat w/ pool
Aug 24 – 31
Guest house rentals with a washer and dryer
Guesthouse in Beaufort
4.8 out of 5 average rating, 186 reviewsSanctuary Cottage- Social Distancing Destination
Apr 29 – May 6
Guesthouse in Beaufort
4.88 out of 5 average rating, 111 reviewsParadise Blue, bright, airy carriage house in town
Jan 3 – 10
Guesthouse in Beaufort
4.98 out of 5 average rating, 199 reviewsBuddy's Cottage near everything in Beaufort, SC
Nov 16 – 23
Guesthouse in Beaufort
4.98 out of 5 average rating, 359 reviewsThe Wren Guest House
Feb 23 – Mar 2
Guesthouse in Beaufort
4.64 out of 5 average rating, 22 reviewsCozy Pet Friendly 1/1 Guest House + Shared Yard
Aug 24 – 31
Guesthouse in Summerville
4.86 out of 5 average rating, 29 reviews1 Bed Detached Guest House, No Smokers, No Animals
Sep 10 – 17
Guesthouse in Summerville
4.98 out of 5 average rating, 52 reviewsHearts & Dreams Peaceful Family Retreat w/ pool
Aug 24 – 31
Guesthouse in Beaufort
5.0 out of 5 average rating, 58 reviewsLow-country Carriage House
Sep 23 – 30
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