House vacation rentals in Colleton County
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Top-rated house rentals in Colleton County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Colleton County house rentals
House rentals with a pool
Home in Beaufort
4.89 out of 5 average rating, 146 reviewsEstate Living on 5 acres with pool in Beaufort, SC
Oct 24 – 31
Home in Saint Helena Island
4.88 out of 5 average rating, 32 reviewsSeaside Bungalow With Million Dollar Views
Jan 9 – 16
Home in Beaufort
4.97 out of 5 average rating, 38 reviewsPrivate Hot Tub + Pool @ Mossy Oaks Nature Retreat
Aug 5 – 12
Home in Edisto Island
5.0 out of 5 average rating, 26 reviewsJungle House/ Pet Friendly/ Luxury New Edisto Home
Jan 25 – Feb 1
Home in Saint Helena Island
5.0 out of 5 average rating, 21 reviewsSteps From Beach With Ocean View
Jan 10 – 17
Home in Saint Helena Island
4.87 out of 5 average rating, 52 reviewsBig Golf Cart! Elevator! Views! Pets! Accessible!
Feb 14 – 21
Home in Edisto Island
4.85 out of 5 average rating, 13 reviewsEdisto Hidden Oasis
Feb 1 – 8
Home in Edisto Island
4.91 out of 5 average rating, 57 reviewsSandpiper Dream - Walk To The Beach + Pool Access!
Dec 3 – 10
Weekly house rentals
Home in Edisto Island
4.93 out of 5 average rating, 174 reviewsTranquility
Jan 17 – 24
Home in Beaufort
4.94 out of 5 average rating, 126 reviewsNear Downtown Beaufort | 15 min. to Parris Isl.
Oct 20 – 27
Home in Edisto Island
4.89 out of 5 average rating, 366 reviews~Edisto Beach Ocean View Retreat~
Mar 15 – 22
Home in Beaufort
4.99 out of 5 average rating, 146 reviewsDowntown Beaufort- Stylish Renovated Chapel
Aug 1 – 8
Home in Walterboro
5.0 out of 5 average rating, 58 reviewsThe Cozy Casa
Nov 12 – 19
Home in Yemassee
4.97 out of 5 average rating, 72 reviewsJust Like Home! Near Beaufort and Historic Sites
Apr 9 – 16
Home in Summerville
4.97 out of 5 average rating, 35 reviewsGuest House/Villa
Apr 4 – 11
Home in Summerville
5.0 out of 5 average rating, 33 reviewsBeautiful 2 Bedroom cottage in Summerville, SC
Feb 3 – 10
Private house rentals
Home in Beaufort
5.0 out of 5 average rating, 70 reviewsLocation & Charm-Close to Bay, Parris Island/MCAS
Apr 25 – May 2
Home in Summerville
4.98 out of 5 average rating, 80 reviewsSmall, Clean Home: No Smokers, No Animals
Jul 24 – 31
Home in Cottageville
5.0 out of 5 average rating, 33 reviewsThe Cardinals Nest - On The Edisto River.
Nov 29 – Dec 6
Home in Beaufort
4.96 out of 5 average rating, 26 reviewsRetreat in downtown Beaufort/beach pass/bike trail
Nov 15 – 22
Home in Saint Helena Island
5.0 out of 5 average rating, 20 reviewsSerene Treehouse Hideaway - Private Beach
Nov 26 – Dec 3
Home in Beaufort
4.98 out of 5 average rating, 84 reviewsBelle Monte (beautiful mountain) on the water!
Jul 14 – 21
Home in Saint Helena Island
4.99 out of 5 average rating, 91 reviewsThe Tidewatch: Beachfront Retreat on Harbor Island
Jan 18 – 25
Home in Beaufort
4.94 out of 5 average rating, 16 reviewsPeaceful Cottage on the Marsh, Close to Downtown
Nov 9 – 16
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