House vacation rentals in La Mesa
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Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa house rentals
House rentals with a pool
Home in La Mesa
4.93 out of 5 average rating, 110 reviewsUpdated TownHome, Great Location, Fantastic Views
Home in La Mesa
4.87 out of 5 average rating, 138 reviewsThe Queen House
Home in El Cajon
4.97 out of 5 average rating, 136 reviewsBeautiful 3,000 Sq Ft Tropical Oasis
Home in Serra Mesa
5 out of 5 average rating, 151 reviewsMidcentury Lux 4BR home w Pool/Spa/Cabana/Firepit
Home in Alpine
4.98 out of 5 average rating, 125 reviewsRancho Maderas Lodge- Solar Heated Pool, King Bed
Home in La Mesa
4.82 out of 5 average rating, 143 reviewsSunny SD/La Mesa Updated '24-Pool-4 bed-Sleeps 10
Home in San Diego
4.91 out of 5 average rating, 127 reviewsSan Diego Getaway W/Pool & Hot tub! Sleeps 8!
Home in El Cajon
4.98 out of 5 average rating, 103 reviewsTop hills, luxury, Sunset View, 4 BR, Pool/Spa
Weekly house rentals
Home in San Diego
4.98 out of 5 average rating, 404 reviewsPrivate Home with Sweeping Views!
Home in La Mesa
4.91 out of 5 average rating, 101 reviews(Relist!) Relax at a Stunning 1931 Historic Tudor!
Home in La Mesa
4.9 out of 5 average rating, 149 reviewsClassic Mid-Century Mount Helix Home with Views
Home in Talmadge
4.98 out of 5 average rating, 292 reviewsPenny's Place: Modern Oasis w Gorgeous Yard
Home in El Cajon
4.95 out of 5 average rating, 314 reviewsPrivate Vineyard Estate w/ Guest House & Hot Tub
Home in Spring Valley
4.81 out of 5 average rating, 225 reviewsROMANTIC AND SPACIOUS JACUZZI SUITE!
Home in City Heights
4.91 out of 5 average rating, 166 reviewsCute Small House
Home in Lemon Grove
4.88 out of 5 average rating, 154 reviewsSpacious 1 bedroom with full size kitchen& living!
Private house rentals
Home in Mission Hills
4.89 out of 5 average rating, 878 reviewsRomantic Private Canyon Retreat
Home in La Mesa
4.84 out of 5 average rating, 131 reviewsLa Mesa's Tranquility
Home in North Park
4.86 out of 5 average rating, 161 reviewsPrivate cottage walkable to restaurants and bars
Home in La Mesa
4.88 out of 5 average rating, 34 reviewsCasita De Grossmont Pool House
Home in La Mesa
4.97 out of 5 average rating, 58 reviewsCozy, Single Bedroom, Detached Guest House
Home in Del Cerro
5 out of 5 average rating, 19 reviewsNewly Decorated Private Suite With Pool
Home in El Cajon
4.98 out of 5 average rating, 95 reviewsSuite Charles Way: A Cozy Fletcher Hills Studio
Home in La Mesa
5 out of 5 average rating, 49 reviewsEscape to tranquility: the perfect retreat
Quick stats about house rentals in La Mesa
Total rentals
280 properties
Rentals with dedicated workspaces
170 properties have a dedicated workspace
Rentals with a pool
80 properties have a pool
Pet-friendly rentals
90 properties allow pets
Family-friendly rentals
190 properties are a good fit for families
Total number of reviews
9.5K reviews
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